Designing Sleeping Sickness Control

Tsetse Control and Gambian Sleeping Sickness; Implications for Control Strategy

BACKGROUND Gambian sleeping sickness (human African trypanosomiasis, HAT) outbreaks are brought under control by case detection and treatment although it is recognised that this typically only reaches about 75% of the population. Vector control is capable of completely interrupting HAT transmission but is not used because it is considered too expensive and difficult to organise in resource-poor...

Sleeping Sickness Wakes Again

Sleeping sickness of horses was, as reeentiy as the IQSO's, the most devastating livestock disease in the United States. Horses died by the hundreds of thousands in the Midwestern United States, in California, and along the Atlantic seaboard at a period which coincided with the beginning of the sharp decline in the use of horses on the farm. Losses were so severe in some areas that the inevitab...

Crisis, what crisis? Control of Rhodesian sleeping sickness.

There is an urgent need for cost-effective strategies for the sustainable control of Trypanosoma brucei rhodesiense (Rhodesian) sleeping sickness, which is a fatal zoonotic disease that has caused devastating epidemics during the past century. Sleeping sickness continues to be controlled by crisis management, using active case detection, treatment and vector control - activities that occur only...

Tsetse Control and the Elimination of Gambian Sleeping Sickness

1 Liverpool School of Tropical Medicine, Liverpool, Merseyside, United Kingdom, 2 IRED, B. P. 433, N'Djaména, Chad, 3 IRD, UMR 177 IRD-CIRAD INTERTRYP, PNLTHA-Ministère de la Santé, Conakry, Republique de Guinee, 4 PNLTHA, Ministère de la Santé, Conakry, Republique de Guinee, 5 Bill and Melinda Gates Foundation, Seattle, Washington, United States of America, 6 Institut Pierre Richet / Institut ...

Sleeping sickness – human African trypanosomiasis